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In contrast, tirzepatide, a dual GIPR/GLP-1R agonist, has been approved for the treatment of T2DM and additionally produces significant weight loss (Le Roux et al., 2023)
Because we want to treat the world, and we want to treat obesity as a whole and for long term
Thicken skin, improve elasticity
Pioglitazone protects pancreatic cells so they produce insulin for longer
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