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The main options currently available include: Orlistat (Alli, Xenical): A lipase inhibitor that reduces dietary fat absorption in the gut
These medications are designed for people who meet certain health criteria, but only tirzepatide currently has FDA-approved guidelines, and those depend on the brand prescribed
Both of these symptoms can lead to more acid in the esophagus and irritate it, which can be painful and cause a burning sensation
A caveat worth noting is that the 2025 trial compared the maximum Zepbound dose (15 mg) with the highest Wegovy doses available at the time (1.7 mg or 2.4 mg)
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