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The Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) tool was used to assess the certainty of the evidence for the two primary biochemical outcomesserum vitamin B12 concentration increase and homocysteine reductionacross all included studies, and separately for randomised controlled trials (RCTs) and observational studies

However, it can be manifested with the classical form of malarial fever, cerebral malaria, or malaria-induced anemia (MIA) and is responsible for one-third of malaria-associated deaths [401]

6 ClinicalTrials.gov REDEFINE 1 (NCT05567796)Registry record for the pivotal phase 3 CagriSema weight-management trial in adults without type 2 diabetes

Mitochondrial dysfunction is both a consequence and driver of secondary injury after TBI (Thapa et al., 2021)