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Results, published in September 2025 in The New England Journal of Medicine , show that high-dose oral semaglutide tablets (25 mg) led to an average weight loss of about 1417% over a little more than a year , along with additional benefits like lower blood pressure and reduced inflammation
However, the results of its use are seen primarily in people with excessive body weight and such effects help with weight loss, not fat burning
Data gaps in smaller markets are bridged with regional analogs indexed to purchasing power parity
And, most recently, an analysis of the electronic health records of 817,309 patients with a history of AUD from January 2014 to August 2022 found that those taking GLP-1s experienced lower rates of alcohol intoxication
