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Bringing this back to homocysteine, it is known that when homocysteine is elevated in the blood, its precursor, S-adenosylhomocysteine, is elevated intracellularly
Other efficacy outcomes, including the proportion of patients reaching weight loss of 5% and change from baseline in lipoproteins, total cholesterol, triglycerides, and blood pressure, are available in the Supplementary Material, Sect
Long-term effects unknown : While the clinical trials look good, the long-term safety and efficacy of tirzepatide, especially for weight loss, is still being studied
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