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In diazepam chronically treated mice, it attenuated diazepam tolerance (provoked by later acute administration of diazepam together with convulsant) and postponed physical dependence/withdrawal effects (provoked by later administration of isoniazid)

The annoying-but-common ones Fatigue - common in the early weeks and while eating much less Headaches - often tied to dehydration or low food intake Dizziness - frequently from not eating or drinking enough A lot of these trace back to the fact that you are suddenly eating and drinking less

Some researchers report stable results up to 45 or 60 days, but 28 days is the window within which potency is most reliably maintained

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