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Feb 16 2019;694:192-197
There is no generic version, and all other versions of PT-141 are not under any regulation for quality or safety
Also, 500 mcg is pretty low, and since the half-life is short, it really should be dosed twice a day
Its sequence AcNlecyclo[AspHisDPheArgTrpLys]NH incorporates a norleucine substitution, a Dphenylalanine substitution, and a lactam bridge that cyclises the molecule, conferring markedly greater stability and resistance to enzymatic degradation than the native linear hormone
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