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Lees studies are smaller than most rigorous clinical trials, ranging in size from two to 16 study participants, and dont include comparison groups
Whilst their primary therapeutic targets are glycaemic control and weight reduction, their brain-mediated effects contribute significantly to clinical outcomes and adverse effect profiles
Sensitivity of malignant peripheral nerve sheath tumor cells to TRAIL is augmented by loss of NF1 through modulation of MYC/MAD and is potentiated by curcumin through induction of ROS
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