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GLP-1/GIP weight loss therapy refers to treatment with tirzepatide, a dual receptor agonist that activates both glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors in the body
In these mechanisms, an immunosuppressive TME is collectively constructed, where lactate further reinforces tumor immune escape by activating GPR81 receptor and regulating metabolic enzymes (e.g., p300) (102) ( Figure 2 )
Basic things such as shifting meal times or collaborating with a doctor to alter the dose can go a long way
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