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(Intrinsic factor is made by cells in the lining of the stomach and is needed for vitamin B12 to be absorbed.) Pernicious anaemia is the most common cause of B12 deficiency in Ireland

Smith JP, et al

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Individual mutations of GHSR residues I178 4.60 , L181 4.63 , and F286 6.58 that interact with the octanoyl moiety of ghrelin to alanine led to the decreased affinity of GHSR for ghrelin (Supplementary Fig