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Alternative diabetes treatments include other GLP-1 agonists, SGLT2 inhibitors, or DPP-4 inhibitors as recommended by NICE guidance

Another 14% of users stopped taking the medications specifically due to cost

The FDA has no direct precedent for reviewing a glucagon agonist for chronic weight management

In contrast, anorexigenic intestinal peptides as peptide YY (PYY), pancreatic polypeptide (PP), GLP-1, oxyntomodulin and cholecystokinin are low during the fasting period, and their level increases after a meal, and some of them are released proportionally to the amount of calories ingested (Reviewed in [127])