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Pfizer's daily pill, danuglipron, was scrapped after one study participant developed liver problems and recovered after they stopped taking the drug
The issue is often bioavailability, not dosage
Some people experience constipation due to reduced motility, while others develop diarrhoea due to bacterial overgrowth from prolonged food retention
Higher concentrations can actually improve stability in some cases because the peptide molecules essentially buffer each other, but they also create more opportunity for aggregation under heat stress
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