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A clinical trial for diabetes that pit orforglipron, a diabetes and weight-loss pill developed by Eli Lilly, against oral semaglutide, made by Novo Nordisk, suggests the former pill may have the edge in reducing blood sugar and weight
Cardiovascular effects: Phase 2 trial data indicate that retatrutide was associated with modest increases in resting heart rate, consistent with observations seen with other GLP-1 receptor agonists
A novel interaction of diethyldithiocarbamate with the glutathione/glutathione [PMID: 3019961] Laboratory literature summary: A novel interaction of diethyldithiocarbamate with the glutathione/glutathione peroxidase system
A 2021 phase 2 trial published in The New England Journal of Medicine showed semaglutide 2.4 mg achieved NASH resolution without worsening fibrosis in 59% of patients versus 17% on placebo (Newsome et al., NEJM 2021)
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