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A synthesis of preclinical and population-level evidence now indicates that these agents may influence the development and progression of several OACs, particularly hepatocellular carcinoma (HCC), pancreatic cancer, and colorectal cancer (CRC)
prednisone, azathioprine, cyclosporine or mycophenolate mofetil)(Bird, 2026)
Sustainable weight management
Overall, the figure emphasizes that escalating receptor engagementfrom single to triple agonismproduces incremental and clinically relevant gains in glucose control, weight reduction, and metabolic flexibility, redefining therapeutic strategies for obesity and type 2 diabetes
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