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Rules change fast, as seen with semaglutides
The diagnosis is ultimately clinical, supported by laboratory findings rather than defined solely by numerical thresholds
Andersson, Emmanuel Shapira, Biochemical and clinical response to hydroxocobalamin versus cyanocobalamin treatment in patients with methylmalonic acidemia and homocystinuria (cblC), The Journal of Pediatrics, Volume 132, Issue 1, January 1998, Pages 121-124, ISSN 0022-3476, Okuda K, Yashima K, Kitazaki T, Takara I
BPC-157, used rigorously and within the limits of current evidence, is one of the more interesting tools available for addressing that decline at a mechanistic level
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