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This delayed gastric emptying can lead to harder, less frequent stools, particularly during dose escalation or in individuals with pre-existing bowel concerns

The most common CKD diagnoses among the study participants included chronic glomerulonephritis and hypertensive nephropathy, which were present in 25% and 27% of the study cohort, respectively

For individuals with prediabetes or early diabetes, this improved sensitivity may help restore more normal glucose metabolism