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Experimental findings with human T cells isolated from healthy human blood samples indicated that UA not only escalates T cells activation by CD25 expression, but also encourages IL-1 secretion in an NLRP3 inflammasome-dependent manner, while simultaneously promoting T cell proliferation (90)
The enigma of small heat shock protein phosphorylation
For the migration assay, cells were seeded at a density of 1 10 6 cells/mL into the upper chamber of Transwell filters (8 m pore size, Corning)
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