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Key points Increased intestinal permeability occurs in a wide range of disorders, including inflammatory bowel disease, coeliac disease and graft-versus-host disease, but the relative contributions of barrier dysfunction and immune responses are unclear
More substantial improvements, if they occur, generally become apparent between months four and six
Signs that you may need a B12 shot include fatigue, pale skin, weakness, shortness of breath and loss of appetite
The underlying anemia can also cause paleness
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