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A compromised gut barrier is associated with reduced GLP-1 signaling efficacy
Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management under the brand name Mounjaro and for chronic weight management as Zepbound
Particularly, NASH and CKD are areas where successful drug development has been challenging, and a new effective treatment could be a significant revenue driver
Compounded medicines are pharmacy-prepared versions of drugs made for individual patients, typically when a licensed product cannot meet a specific clinical need
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