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Abstract Introduction Melanocortin 4 receptor (MC4R) is a G-protein-coupled receptor expressed in the hypothalamus, playing a key role in regulating feeding behavior and energy homeostasis
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The peptides I am referring to in this article are unapproved synthetic peptides that are engineered to mimic naturally occurring hormones
We next considered the potential role of neoantigens resulting from SNVs in early disease by predicting neoantigens for patient-specific HLA-A, -B and -C alleles using NetMHC4.0 31,32 (see Supplementary Methods) and examining the loss of these predicted neoantigens due to LOH in late disease
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