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The authors noted NNMT overexpression in many human malignancies and described 5-Amino-1MQ as a novel NNMT inhibitor with promising results across obesity and cancer cell research models
With various forms of cell death observed in CKD, such as necroptosis, apoptosis, and autophagy, the question of whether ferroptosis predominates in kidney disease and whether multiple modes of cell death interact with each other needs to be emphasized and addressed
This was just confirmed by my colleague, Keith Humphreys, at Stanford
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