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Traditional treatment modalities, including medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside psychotherapy and peer support, remain essential pillars of care

Restoring mitochondrial OXPHOS has thus emerged as a promising therapeutic strategy

In healthy individuals, GLP-1 is released after food consumption, particularly in response to proteins and fats, signaling satiety and stimulating insulin secretion

[4] Long-acting GLP-1 receptor agonists offer less frequent dosing and include: Dulaglutide (Trulicity) : Once-weekly injection, available in single-dose pens ranging from 0.75 mg to 4.5 mg Semaglutide (Ozempic, Wegovy) : Once-weekly injection