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Varela MC, Kok F, Setian N, Kim CA, Koiffmann CP : Impact of molecular mechanisms, including deletion size, on Prader-Willi syndrome phenotype: study of 75 patients
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Moreover, combination therapies have demonstrated significant advantages, such as Novo Nordisks CagriSema (semaglutide + cagrilintide), which shows superior glycemic control and weight reduction effects compared to semaglutide alone, demonstrating that combination therapy can achieve more than the sum of its parts while reducing side effects
The Leerink analysts expect CagriSema to demonstrate best-ever weight loss any day now, adding that we expect at least high-20% weight loss. Still, CagriSema could pose practical challenges for Novo, particularly in terms of commercialization
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