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New England Journal of Medicine (2025) The REDEFINE 2 Phase 3 trial evaluated CagriSema in 1,206 adults with overweight or obesity and type 2 diabetes in a 68-week, double-blind, placebo-controlled design
CJC-1295 and ipamorelin are peptides that work to stimulate the pituitary gland to release natural growth hormone, supporting recovery, fat metabolism, and sleep
That's a clinically meaningful result - it's larger than what any prior obesity pharmacotherapy had achieved at scale
The practice took off in the summer of 2024
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