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This liver fat reduction likely reflects the combined action of GIP-mediated fat metabolism and glucagon-driven lipolysis, both of which reduce hepatic lipid accumulation through distinct but complementary mechanisms
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In addition to initial FLOW trial findings indicating Ozempic can offer kidney protective benefits, results of Novo Nordisks SELECT trial showed that semaglutide significantly reduced rates of kidney and cardiovascular events compared with placebo in participants with overweight and obesity with cardiovascular disease but without diabetes
Faster breakdown The enzyme DPP-IV destroys GLP-1 quickly, shortening how long it can work
