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All candidates require a thorough medical evaluation, with careful screening for renal failure, hepatic insufficiency, or cardiopulmonary compromise, and close monitoring whenever glycine is administered to anyone with borderline organ function

Nature 600:686689

While both medications belong to the GLP-1 family, Mounjaro (tirzepatide) is a dual GIP and GLP-1 receptor agonist, which means its mechanism of action is slightly different and may lead to different side effect profiles

Moreover, in accordance with what has been discussed above, the lactate secreted by MSCs can not only induce M2 macrophage polarization, but promote the capability of DCs polarizing CD4 + T cells into Th2 cells, implicating the dynamic interaction between M2 macrophages and DCs [104]