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Eligibility is restricted to adults with a BMI of at least 35 kg/m and at least one weight-related comorbidity, or a BMI of 40 or above, who have not achieved meaningful weight loss through nutritional management, and who are under specialist supervision with a lifestyle programme
1996 May;128(5 Pt 2):S32-7
The best approaches to confirm, refute, or refine our findings would be to conduct a much larger, retrospective, multicenter population-based cohort study
For those with significant deficiency, meaningful change in fatigue and cognition typically develops over several weeks as levels normalize
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