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Update on SLC6A14 in lung and gastrointestinal physiology and physiopathology: focus on cystic fibrosis
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However, in resistant patients, oxidative stress causes a conformational change in Keap1, leading to the release of NRF2, which translocates to the nucleus and binds to antioxidant response element (ARE), activating the expression of downstream antioxidant genes, including GPX4, NQO1, HO-1 and SOD1 [33], and promoting the synthesis of GSH, as illustrated in Fig
Glutathione l mt thiol-tripeptide c trng lng phn t thp, ng vai tr ni bt trong vic duy tr cn bng oxy ha kh ni bo
