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In the obesity trial of 48 week-duration, percentage change in body weight from baseline after 24 weeks and 48 weeks were the primary and secondary outcomes respectively

Others say they sleep longer or feel drained throughout the day

women of childbearing potential should use effective contraception) Current opioid use or acute opioid withdrawal , as naltrexone will precipitate withdrawal symptoms Severe hepatic impairment (contraindicated) End-stage renal disease (contraindicated) Abrupt discontinuation of alcohol or benzodiazepines (risk of seizures) Additional cautions apply in the following situations: Moderate hepatic impairment or moderate-to-severe renal impairment: the maximum daily dose must be reduced (refer to the SmPC for specific guidance) Bipolar disorder or a history of mania or hypomania: bupropion may precipitate a manic episode Narrow-angle glaucoma: bupropion may increase intraocular pressure Significant cardiovascular disease: careful assessment is required given the potential for blood pressure and heart rate elevation Drug interactions: bupropion is a potent CYP2D6 inhibitor and can increase plasma concentrations of CYP2D6 substrates with a narrow therapeutic index (e.g., certain antidepressants, antipsychotics, beta-blockers, and antiarrhythmics)

Victims of medical negligence in Atlanta can seek compensation for economic damages and non-economic damages