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ALC is a highly bioavailable form of carnitine that can cross the blood-brain barrier, where it helps to neutralise free radicals, supports mitochondrial function and helps to maintain normal neurotransmitter activity

Nox activity also contributes to glial inflammatory response in the brain 6

Early studies indicated that CHAC2 expression was not differentially regulated and was generally higher than that of CHAC1, suggesting a role in the basal turnover of GSH rather than the stress- and signaling-associated functions of CHAC1

Across diverse CNS disease contexts, these agents have reduced inflammatory readouts and improved functional outcomes in vivo [189,190,191]