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As a foundational tool, metabolomics has been widely applied to identify characteristic metabolites in the blood of CRC patients, such as pyruvate, glutamate, and short-chain fatty acids [165]
10.1016/j.mad.2024.111941 13 BoguckaD.WajdaA.StypiskaB.RadkowskiM
Partial correlation and linear regression analysis were employed after systematically controlling the major confounding factors, such as age, gender, calorie intake and physical activity level
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