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Consuming fewer calories than these minimums for extended periods can lead to nutrient deficiencies, muscle loss, metabolic slowdown, and other health complications
1 2 Clinica Chimica Acta
Rashes are uncommon but possible
A 2.6% reduction in hip bone mineral density and a 2.1% reduction at the lumbar spine in 52 weeks (Hansen et al., 2024), combined with up to 10.9% lean mass loss over 72 weeks (Look et al., 2025), means that patients on GLP-1 therapy need a comprehensive musculoskeletal protection plan from day one
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