When you swallow a traditional pill, the harsh acids in your stomach can break down the fragile tripeptide before it ever reaches your small intestine for absorption
Specifically, serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were measured to evaluate liver function, while blood urea nitrogen (BUN) and creatinine were measured to assess kidney function
GSH Metabolism, Biosynthesis & Health Implications (PubMed, 2004) Cysteine Availability as the Rate-Limiting Factor in GSH Synthesis A widely cited review of glutathione metabolism published on PubMed documented the two-step cytosolic biosynthesis pathway in detail, confirming that GSH synthesis is regulated primarily by gamma-glutamylcysteine synthetase activity, cysteine availability, and GSH feedback inhibition
It does not: five dose groups of 100102 is roughly 506, and 506 + 99 + 101 = 706, which matches the registrys recorded enrolment of 706 exactly [6]