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Moreover, elevated serum arginase 1 (ARG1) levels are frequently observed in the serum of cancer patients, and are positively correlated with a poor prognosis [273]
It may potentially phosphorylate various target proteins, thus initiating downstream cellular responses
Most patients can restart successfully, especially when beginning at a lower dose and titrating slowly
Those with a personal or family history of medullary thyroid cancer, multiple endocrine neoplasia syndrome type 2, or previous episodes of pancreatitis need thorough medical evaluation before starting treatment
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