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While these medications are not primarily classified as hormonal therapies, their metabolic effects inevitably intersect with endocrine function, particularly in patients with obesity and insulin resistanceconditions known to disrupt multiple hormonal axes

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Modulation of GH secretion may enhance anabolic processes in liver and muscle, partially counteracting catabolic effects [33]

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Tryptophan is one of the essential amino acids in the human body and is decomposed mainly through the kynurenine pathway, in addition to producing physiologically active substances, such as 5-hydroxytryptamine and melatonin

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