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Two different DHAR isoforms have been discovered in Spinacia oleracea leaves with one isoform located in chloroplasts whereas the other being present in the sub-cellular compartment other than chloroplasts (Shimaoka et al., 2000)

Here's what's crucial to understand: while the peptides themselves may not have specific FDA approval for certain conditions, the facilities producing them are regulated

Given the impaired lysosomal acidification observed in our partial v-ATPase-deficient model, we investigated the assembly status of the v-ATPase

Such experiments would provide a more direct assessment of mitochondrial impairment