Pharmaceuticals (Basel) 17(12):1655 Picoli CC, Tsibulnikov S, Ho M, Demambro V, Feng T, Eltahir M, Le PT, Chlebek C, Rosen CJ, Ryzhov S, Li Z (2025) Vertical sleeve gastrectomy and semaglutide have distinct effects on skeletal health and heart function in obese male mice
Clinical trials have provided limited insight into the long-term effects, as the longest trials spanned less than six years in adults and about one year in adolescents
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Data points represent the mean of at least three independent experiments