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Where it works: Adipose tissue (fat cells): Reduces inflammation and may improve fat metabolism Pancreas: Works alongside GLP-1 to enhance insulin secretion Brain: May contribute to appetite regulation (research ongoing) Weight loss contribution: When GIP is added to GLP-1 (as in tirzepatide), weight loss increases from ~15% to ~22%
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Plus, while our bodies can produce some antioxidant compounds, production of those antioxidants naturally declines with age
The addition of glucagon receptor agonism may enhance energy expenditure and fat oxidation, contributing to greater weight loss.
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