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His doctor warned against GLP-1s because of their effects on muscle loss
When to contact your GP: Persistent or severe nausea/vomiting preventing adequate fluid intake Severe, persistent abdominal pain which could indicate pancreatitis New or worsening depression, anxiety, or suicidal thoughts Severe headaches or visual disturbances Unexplained cognitive changes or confusion Signs of hypoglycaemia (if taking alongside insulin or sulfonylureas) NICE guidance recommends regular monitoring during GLP-1 receptor agonist therapy
doi:10.1001/jamaophthalmol.2024.2296.
Clinical data from the STEP 1 extension study show that most patients experience weight regain after discontinuation, with research indicating that on average, approximately two-thirds of lost weight returns within one year of stopping treatment
