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Liver (hepatic) and kidney safety considerations are equally important, since some supplements that undergo hepatic metabolism or renal excretion can accumulate or interact with chemotherapeutic drugs leading to hepatotoxicity (e.g., kava, high-dose green tea extract) or nephrotoxicity in patients who already suffer from impaired organ function or taking chemotherapy agents known to be nephrotoxic such as cisplatin (208, 209)

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Tips Topical medication should be applied to the entire affected area, not just individual pimples

Among them, temperature, salinity, inorganic salts (especially ammonia nitrogen and nitrite) and pH are important parameters