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Taking arginine metabolism as an example, myeloid cells in the tumor microenvironment, including tumor-associated macrophages and myeloid-derived suppressor cells, often suppress effector immunity through ARG1/ARG2-mediated arginine depletion
A recommendation isn't the finish line
A 2019 FDA warning letter to a compounding pharmacy cited glutathione IV formulations as 'misbranded drugs'not because the molecule itself is illegal, but because the delivery method and marketing claims crossed regulatory lines
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