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Meanwhile, for patients seeking FDA-approved weight-loss medicines, tirzepatide (Zepbound / Mounjaro) and semaglutide (Wegovy / Ozempic / Rybelsus) are presently among the most effective and studied options
Nevertheless, metformin remains the typical first-line choice because of its well-established safety profile, efficacy, low cost, and wide accessibility (Wexler 2021b)
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GLP-1 analog attenuates cocaine reward
It works by mimicking a GLP-1 hormone in your gut that helps regulate blood sugar, slows digestion, and reduces appetiteoften leading to noticeable weight loss
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