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GLP-1 receptor agonists work by increasing the levels of the hormone GLP-1 in the body, which helps to increase the bodys sensitivity to insulin and reduce hunger
Both semaglutide and tirzepatide can help lower inflammation levels in the body
It's been called a "life changer" and the "key to staying lean." That excitement isn't entirely unfounded: in clinical trials, retatrutide has produced some of the most dramatic weight-loss results researchers have seen from an obesity medication
The RENAAL trial (N=1,513, mean follow-up 3.4 years) showed losartan reduced the risk of doubling serum creatinine by 25% compared to placebo over the long term, demonstrating net kidney protection despite the early apparent rise
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