It simultaneously restores gut microbiota balance, enriching beneficial bacteria such as Lactobacillus while suppressing harmful species
Similarly, the SURMOUNT-4 trial showed substantial weight regain following tirzepatide discontinuation
While ok in the short term, long term, significant nutrient, protein and calorie intake puts you at higher risk of certain conditions, including bone loss (osteoporosis), a compromised immune system, hair loss, compromised cell health, nutrient deficiencies, weakness & fatigue, hormonal imbalances, cognitive impairment and sleep disturbances
8 Direct action on the skin is a possible mechanism, as GLP-1Rs have been shown to be expressed in the skin of newborn mice and cultured skin cells