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While these effects are generally manageable, they represent more pronounced GI side effects than observed with AOD-9604
The lysine-proline-valine sequence binds to MC1R on immune cells including macrophages, mast cells, and T-lymphocytes, triggering downstream inhibition of nuclear factor kappa B (NF-B)the transcription factor responsible for upregulating pro-inflammatory cytokines including TNF-, IL-6, and IL-1
Limitations: The interaction between the four peptides in a single blend has not been formally studied from a toxicological standpoint
Animal studies suggest it may accelerate repair of muscle, tendon, and ligament injuries while reducing inflammation and soreness, allowing faster return to training
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