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Moreover, we validated the relationship between GSH-regulated replication stress and JMF4073 sensitivity in a number of TKI-insensitive human CML blast-crisis cells, and present the evidence of the synthetic lethality by targeting glutathione biosynthesis with JMF4073 in these cells
L-Carnitine-L-Tartrate 1000 mg, Co-Enzyme Q10 60 mg, Zinc (as Elemental Zinc) 12.5 mg, and Lycopene 2500 mcg Capsules are a nutritional supplement formulated to support energy production, antioxidant defense, and overall vitality
Compounds are not for human consumption, diagnostic use, or therapeutic application
The maximum dose studied in clinical trials is 12 mg once weekly
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