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However, the understanding on the molecular mechanism of HGP is still limited
Mayo KE, Miller LJ, Bata ate D, et al.: International Union of Pharmacology
Following FOXO4 displacement, the released p53 undergoes nuclear export and mitochondrial translocation, activating the intrinsic apoptosis pathway via BAX upregulation and BCL-2 downregulation, culminating in caspase-3 cleavage and apoptotic cell death
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