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PMID 8598105.

Apart from external inducers, endogenous triggers such as mast cell-derived histamine, proteases and eicosanoids can increase intestinal permeability, either directly or via stimulation of neurons of the enteric nervous system [194],[199],[200]

Together with the inward movement of the extracellular part of TM5, they push the N-terminus of GLP-2 away from TM5 to reside closely with TM3, where H268 3.37b contributes a hydrogen bond to stabilize the conformation (Supplementary information, Fig

Sua principal funo transportar cidos graxos para dentro das mitocndrias, as fbricas de energia das clulas, onde so queimados para produzir ATP (adenosina trifosfato), que a principal fonte de energia celular