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Diabetes Care 39 , 988995 (2016)

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Safety Prior to randomization, one patient (of 224 enrolled participants) died, with no relationship between the death and the study or the supplement identified by the CIMATEC committee, since the death occurred prior to collect blood samples or consume the investigational supplement

Spacing doses further apart, consuming electrolyte-enhanced fluids between meals, and eating five to six small portions daily instead of three meals often resolves protracted nausea