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To date, these GLP-1 drugs have been approved to treat three adult populations: individuals with type 2 diabetes, individuals with a body mass index (BMI) of 30 or greater (obesity), and individuals with a BMI between 27 and 30 (overweight) with at least one weight-related health condition, such as cardiovascular disease, high blood pressure, high cholesterol, prior stroke, prior heart attack, and chest pain (angina)
doi: 10.1517/17425247.2015.1001362 278 BollingerKWMhUOciusKLApostolosAJPiresMMHelmRFet al
Amgen is developing a GLP-1/GIP dual agonist called MariTide (currently in phase 3 trials expected to complete in 2027), which is administered as a once-monthly injection
It should not be overstated into CJC-1295 kills that claim is unsupported nor waved away, because a halted trial with a death is a meaningful signal about how little is known
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